this is a minefield. I suggest you invest some money and go and see a good accountant who will point you in the right direction. Also the revenue office is very useful.
You will need to make sure that you have the correct employment contracts in place for employed staff. The Pay As You Earn tax process is then a very straightforward matter. As mentioned before, the Inland Revenue will be able to assist with this and will give you all the information that you need. If you are planning to have self employed staff there then, again a proper contract for services will be required to make sure that you don't become liable to pay tax on their earnings. This is again, a straightforward matter to put in place. One other thought as well is with regard to training schemes and apprenticeships and you should make sure that you take full advantage of the benefits that these can give to your business.
I am currently working with a hair salon putting all of this in place so, if you want some further advice about this please let me know and I will be happy to discuss matters with you in more detail.
thank you All for your responses, much appreciated. Jenny l have noted your contact detail.. in the event all goes well!! Regards Dawn